THE POS88 SLOT DIARIES

to check the impact of many constraints on mutational tolerance during selection, we chose E. coli dihydrofolate reductase (DHFR) as being a product process. DHFR is an essential enzyme in folate metabolism that cuts down dihydrofolate to tetrahydrofolate and is needed for thymidine manufacturing. making use of this exercise as The premise for an i